Publication
- Nakamura S, Inoue K, Takahashi K, Maeda S, Fujii T. Heterogeneous Treatment Effects of Renal Replacement Therapy in Critically Ill Patients: A Multicenter Observational Study Using a Japanese ICU Registry. Crit Care Med. 2026;54(10):2590-2600.
- Goto S, Okano H, Okamoto H. Age-related modification of the association between arterial blood pH and intensive care unit mortality: a nationwide retrospective observational study using the Japanese Intensive Care Patient Database (JIPAD). J Intensive Care. 2026;14(1):104.
- Maeda S, Yamamoto R, Fujii T. Trends in renal dysfunction, renal replacement therapy, and mortality in intensive care units: A nationwide Japanese ICU database study. Anaesth Crit Care Pain Med. 2026; Online ahead of print.
- Ohbe H, Kumasawa J, Okamoto H, Hashiba E, Ohshimo S, Tagami T, et al. Validation of the Diagnosis Procedure Combination Database in Japan for ICU Research: A Multicenter Comparison With the Japanese Intensive care PAtient Database (JIPAD). J Epidemiol. 2026;36(9):289-297.
- Miyazaki R, Okano H, Goto S, Tanaka H, Okamoto H. Severity and Clinical Outcomes Among ICU Patients With Diabetic Ketoacidosis: An Analysis of the Japanese Intensive Care Patient Database. Crit Care Explor. 2026;8(8):e1449.
- Sekiya S, Goto S, Okano H, Okamoto H. Aspiration pneumonia in the world's most aged society: age-stratified ICU management and outcomes from a nationwide Japanese registry. J Intensive Care. 2026;14(1):93.
- Kikutani K, Nishikimi M, Kyo M, Yamaga S, Shimatani T, Ota K, et al. Risk Stratification Using the Tracheostomy Early Prediction Score and the Association Between Early Tracheostomy and Mortality in Sepsis. Respir Care. 2026; Online ahead of print.
- Yawata S, Uchino S, Yamashima S, Nishiyama S, Ono S, Sasabuchi Y, et al. Association between ICU-level variation in arterial blood gas utilization and in-hospital mortality: A retrospective cohort study using the Japanese Intensive care PAtient Database registry. PLoS One. 2026;21(6):e0343186.
- Endo H, Hashimoto S. Development and validation of a prediction model of length of ICU stay for benchmarking: a retrospective cohort study. Sci Rep. 2026;16(1):25326.
- Shiotsuka J, Uchino S, Sasabuchi Y, Imahase H, Masuyama T, Ono S, et al. Institutional Variation in Life-Sustaining Treatments and Mortality Among Older Patients. JAMA Health Forum. 2026;7(6):e261451.
- Mizobuchi Y, Aoki Y, Kobayashi K, Katsuragawa T, Niwa T, Oshima S, et al. Intensive care utilization and clinical outcomes after transcatheter aortic valve implantation: a nationwide observational study using the Japanese intensive care patient database. Heart Vessels. 2026; Online ahead of print.
- Hayakawa K, Yamaguchi K, Sugita M. Characteristics and prognostic factors of adult poisoning patients in the intensive care unit: A retrospective cohort study using the Japanese intensive care patient database. Toxicol Rep. 2026;16:102264.
- Pari V, Pilcher D, Pisani L. Towards a common core dataset for critical care: a registry-centered vision for global improvement. Crit Care Sci. 2026;38:e20260338.
- Aoki Y, Shiko Y, Kawasaki Y, Nakajima M, Oda K, Ubukata K, et al. Extracorporeal Cardiopulmonary Resuscitation for Perioperative Cardiac Arrest in Noncardiac Surgery: A Nationwide Cohort Study in Japan. Anesthesiol Open. 2026;1(1):e0013.
- Aiga S, Uchino S, Nishiyama S, Masuyama T, Sasabuchi Y, Sanui M. Characteristics and short-term outcomes of patients with hematological malignancies admitted to Intensive care units: a retrospective cohort study using the Japanese Intensive care PAtient Database. Anaesth Crit Care Pain Med. 2026;45(2):101652.
- Goto S, Okano H, Okamoto H. Early postoperative factors associated with in-hospital mortality after emergency noncardiac surgery: A Japanese nationwide registry-based intensive care unit cohort study. Sci Rep. 2026;16(1):11041.
- Maezawa T, Sakuraya M, Takaba A. Temporal trends in post-extubation respiratory management and reintubation risk factors in Japan: A retrospective multicenter cohort study. Crit Care Resusc. 2026;28(1):100170.
- Kumasawa J, Okamoto H, Naito T, Asaga T, Kimura M, Kotani T, et al. Development and 2025 re-evaluation of a Japanese quality indicator set for adult intensive care: a modified RAND/UCLA Delphi study. J Intensive Care. 2026;14(1):29.
- Maezawa T, Sakuraya M, Goto T. The relationship between a lower body mass index and reintubation among critically ill patients: a multicenter retrospective cohort study. J Anesth Analg Crit Care. 2026;6(1):39.
- Takeda C, Sakuraya M, Tanaka-Mizuno S, Sakurai K, Kai S, Mizota T, et al. Impact of the ICU admission of patients with COVID-19 on the outcomes of patients without COVID-19 in the ICU: a retrospective cohort study. J Anesth. 2026;40(1):69-77.
- Pisani L, Di Lecce P, Sendagire C, Pari V, Olivieri C, Uddin RAME, et al. Characteristics of intensive care unit registries - findings from the Global Registry ICU Datasets (GRID) survey. Crit Care Sci. 2026;38:e20260168.
- Ranzani OT, Singer M, Salluh JIF, Shankar-Hari M, Pilcher D, Berger-Estilita J, et al. Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score. JAMA. 2025;334(23):2090-2103.
- Arita Y, Kawakami D, Koga H, Yoshino S. What Is the Optimal Reintubation Rate?: A Multicenter Retrospective Study. Chest Crit Care. 2025;3(4):100210.
- Aoki Y, Shimizu M, Nakajima M, Ota K, Kaszynski RH, Naruse S, et al. Association Between Activation of a Rapid Response Team and Outcomes of Sepsis in General Wards: A Nationwide Observational Study Using the Japanese Intensive Care Patient Database. Crit Care Med. 2025;53(12):e2458-e2467.
- Anezaki H, Aoki Y, Kato H, Nakajima M, Kaszynski RH, Suzuki K, et al. Perioperative cardiac arrest requiring admission to intensive care units in Japan: epidemiological differences between emergency and elective surgery from a multicentre cohort study. Br J Anaesth. 2025;135(6):1654-1662.
- Kikutani K, Nishikimi M, Kyo M, Yamaga S, Shimatani T, Ota K, et al. Development and validation of the STeP score for predicting tracheostomy in patients with sepsis using a nationwide ICU database: a retrospective observational study. J Intensive Care. 2025;13(1):64.
- Omoto M, Aoki Y, Nakajima M, Kurita T, Kaszynski RH, Kato H, et al. Epidemiological Investigation of Unplanned Intensive Care Unit Admissions From the Operating Room After Elective Surgery: A Nationwide Observational Study in Japan. Anesth Analg. 2025;141(5):998-1006.
- Sakuraya M, Sugimoto T, Kikutani K, Takeda C, Kasugai D, Okano H, et al. Association of Medical Burden and Capacity Changes With Clinical Outcomes Among Patients Without COVID-19 During the Pandemic: A Multicenter Retrospective Cohort Study. Crit Care Med. 2025;53(10):e1918-e1929.
- Aoki Y, Nakajima M, Mimuro S, Imai R, Katsuragawa T, Kobayashi K, et al. Association between postoperative body temperature and in-hospital mortality: a nationwide cohort study of 157,028 critically ill patients in Japan. Can J Anaesth. 2025;72(9):1367-1378.
- Ohbe H, Kudo D, Kobayashi N, Shirasaki K, Nakamura K, Iwashyna TJ, et al. Timing of onset of persistent critical illness in Japan: a nationwide registry study. Lancet Reg Health West Pac. 2025;60:101632.
- Tohyama T, McCoy LG, Ishii E, Sood S, Raffa J, Kinoshita T, et al. Mortality Prediction Performance Under Geographical, Temporal, and COVID-19 Pandemic Dataset Shift: External Validation of the Global Open-Source Severity of Illness Score Model. Crit Care Explor. 2025;7(6):e1275.
- Okano H, Okamoto H, Tanaka H, Sakurai R, Yamazaki T. Comparison of intermittent and continuous renal replacement therapy for sepsis-associated AKI: a retrospective analysis of the Japanese ICU database. JA Clin Rep. 2025;11(1):24.
- Masaki H, Suzuki S, Nakayama N, Kobayashi E, Fujii A, Nishiwaki K, et al. Risk markers for postoperative reintubation of intensive care unit patients: A retrospective multicentre study of the National Intensive Care Registry. Intensive Crit Care Nurs. 2025;87:103956.
- Shiotsuka J, Masuyama T, Uchino S, Sasabuchi Y, Suzuki R, Ono S, et al. Utilization and outcomes of life-supporting interventions in older ICU patients in Japan: a nationwide registry study. Intensive Care Med. 2025;51(1):115-124.
- Suzuki Y, Aoki Y, Shimizu M, Nakajima M, Imai R, Okada Y, et al. Predictive accuracy of lactate albumin ratio for mortality in intensive care units: a nationwide cohort study. BMJ Open. 2024;14(12):e088926.
- Nosaka N, Anzai T, Wakabayashi K. Height status matters for risk of mortality in critically ill children. J Intensive Care. 2024;12(1):42.
- Endo H, Okamoto H, Hashimoto S, Miyata H. Association Between In-hospital Mortality and the Institutional Factors of Intensive Care Units with a Focus on the Intensivist-to-bed Ratio: A Retrospective Cohort Study. J Intensive Care Med. 2024;39(10):958-964.
- Azumi M, Mizobuchi Y, Nakanishi N, Nakajima K, Hara K, Fujihara T, et al. Value of the Acute Physiology and Chronic Health Evaluation II (APACHE II) score in predicting hospital mortality for postoperative brain tumor patients in intensive care units in Japan: A retrospective case-control study. Clin Neurol Neurosurg. 2024;244:108435.
- Fujinaga J, Otake T, Umeda T, Fukuoka T. Case volume and specialization in critically ill emergency patients: a nationwide cohort study in Japanese ICUs. J Intensive Care. 2024;12(1):20.
- Shimada H, Matsuoka Y, Miyakoshi C, Ito J, Seo R, Ariyoshi K, et al. Predictive performance of the sequential organ failure assessment score for in-hospital mortality in patients with end-stage kidney disease in intensive care units: A multicenter registry in Japan. Ther Apher Dial. 2024;28(2):305-313.
- Hayakawa K, Uchino S, Endo H, Hasegawa K, Kiyota K. Impact of missing values on the ability of the acute physiology and chronic health evaluation III and Japan risk of death models to predict mortality. J Crit Care. 2024;79:154432.
- Shimizu R, Nakanishi N, Ishihara M, Oto J, Kotani J. Utility of Lean Body Mass Equations and Body Mass Index for Predicting Outcomes in Critically Ill Adults with Sepsis: A Retrospective Study. Diseases. 2024;12(2):30.
- McLarty J, Litton E, Beane A, Aryal D, Bailey M, Bendel S, et al. Non-COVID-19 intensive care admissions during the pandemic: a multinational registry-based study. Thorax. 2024;79(2):120-127.
- Salluh JIF, Quintairos A, Dongelmans DA, Aryal D, Bagshaw S, Beane A, et al. National ICU Registries as Enablers of Clinical Research and Quality Improvement. Crit Care Med. 2024;52(1):125-135.
- Fukano K, Iizuka Y, Nishiyama S, Yoshinaga K, Uchino S, Sasabuchi Y, et al. Characteristics of pulmonary artery catheter use in multicenter ICUs in Japan and the association with mortality: a multicenter cohort study using the Japanese Intensive care PAtient Database. Crit Care. 2023;27(1):412.
- Aoki Y, Nakajima M, Sugimura S, Suzuki Y, Makino H, Obata Y, et al. Postoperative norepinephrine versus dopamine in patients undergoing noncardiac surgery: a propensity-matched analysis using a nationwide intensive care database. Korean J Anesthesiol. 2023;76(5):481-489.
- Asaba H, Aoki Y, Akinaga C, Naruse S, Uchizaki S, Nakajima M, et al. Obstetric admission to intensive care units in Japan: a cohort study using the Japanese Intensive care PAtient Database. J Anesth. 2023;37(4):539-545.
- Ishii E, Nawa N, Hashimoto S, Shigemitsu H, Fujiwara T. Development, validation, and feature extraction of a deep learning model predicting in-hospital mortality using Japan's largest national ICU database: a validation framework for transparent clinical Artificial Intelligence (cAI) development. Anaesth Crit Care Pain Med. 2023;42(2):101167.
- Nosaka N, Anzai T, Uchimido R, Mishima Y, Takahashi K, Wakabayashi K. An anthropometric evidence against the use of age-based estimation of bodyweight in pediatric patients admitted to intensive care units. Sci Rep. 2023;13(1):3574.
- Endo H, Uchino S, Hashimoto S, Ichihara N, Miyata H. Recalibration of prediction model was needed for monitoring health care quality in subgroups: a retrospective cohort study. J Clin Epidemiol. 2023;154:56-64.
- Dongelmans DA, Quintairos A, Buanes EA, Aryal D, Bagshaw S, Bendel S, et al. Worldwide clinical intensive care registries response to the pandemic: An international survey. J Crit Care. 2022;71:154111.
- Namikata Y, Matsuoka Y, Ito J, Seo R, Hijikata Y, Itaya T, et al. Association between ICU admission during off-hours and in-hospital mortality: a multicenter registry in Japan. J Intensive Care. 2022;10(1):41.
- Ohbe H, Endo H, Kumasawa J. Characteristics of COVID-19 in multicenter ICUs in Japan. J Anesth. 2022;36(4):572-573.
- Takekawa D, Endo H, Hashiba E, Hirota K. Predict models for prolonged ICU stay using APACHE II, APACHE III and SAPS II scores: A Japanese multicenter retrospective cohort study. PLoS One. 2022;17(6):e0269737.
- Tanaka A, Uchiyama A, Kitamura T, Sakaguchi R, Komukai S, Matsuyama T, et al. Association between early tracheostomy and patient outcomes in critically ill patients on mechanical ventilation: a multicenter cohort study. J Intensive Care. 2022;10(1):19.
- Suzuki R, Uchino S, Sasabuchi Y, Kawarai Lefor A, Sanui M. Dopamine use and its consequences in the intensive care unit: a cohort study utilizing the Japanese Intensive care PAtient Database. Crit Care. 2022;26(1):90.
- Fujinaga J, Suzuki E, Irie H, Onodera M. Body Mass Index and Ventilator Dependence in Critically Ill Subjects in Japan: A Cohort Study Using a Nationwide Database. Respir Care. 2021;66(9):1433-1439.
- Mochizuki K, Fujii T, Paul E, Anstey M, Uchino S, Pilcher DV, et al. Acidemia subtypes in critically ill patients: An international cohort study. J Crit Care. 2021;64:10-17.
- Endo H, Ohbe H, Kumasawa J, Uchino S, Hashimoto S, Aoki Y, et al. Conventional risk prediction models fail to accurately predict mortality risk among patients with coronavirus disease 2019 in intensive care units: a difficult time to assess clinical severity and quality of care. J Intensive Care. 2021;9(1):42.
- Endo H, Uchino S, Hashimoto S, Aoki Y, Hashiba E, Hatakeyama J, et al. Development and validation of the predictive risk of death model for adult patients admitted to intensive care units in Japan: an approach to improve the accuracy of healthcare quality measures. J Intensive Care. 2021;9(1):18.